Gum cleaning may boost bone health, tiny study hints
NCT ID NCT07438977
First seen Jun 25, 2026 · Last updated Sep 11, 2026 · Updated 3 times
Summary
This study looks at whether non-surgical gum cleaning (scaling and root planing) can change levels of certain bone-related substances in the blood of people with advanced gum disease. Sixteen adults with stage III periodontitis will receive the treatment, and their blood will be tested before and after. The goal is to understand how gum therapy affects bone metabolism, but the study is small and early-stage, so results are preliminary.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Non-surgical periodontal therapy (scaling and root planing)
- What this could lead to
- If successful, this study could help show that gum treatment improves bone health markers in the blood, pointing toward better ways to manage periodontitis.
- What could go wrong
- This is a very small study (16 people) with no control group, so results may not be reliable or apply to others. It only measures blood markers, not long-term health outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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16 people
The number who actually took part.
- Started
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Dec 2024
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 to 65 years * Diagnosed with Stage III periodontitis according to the current periodontal classification * Systemically healthy individuals * Presence of at least 20 natural teeth * Willingness to participate in the study and provide written informed consent Exclusion Criteria: * Presence of systemic diseases that may affect periodontal status or bone metabolism * Use of antibiotics, anti-inflammatory drugs, or medications affecting bone metabolism within the last 3 months * Pregnancy or lactation * Current smokers or history of smoking * Previous periodontal treatment within the last 6 months
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Atatürk University Faculty of Dentistry
Erzurum, Erzurum, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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