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New software could spot dangerous heart blockages without surgery

NCT ID NCT06183294

Diagnosis Sponsor: University of California, San Diego Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new software program that analyzes heart angiogram images to measure blood flow blockages without needing to insert a pressure wire into the artery. Researchers reviewed the records of 100 patients who had both an angiogram and an invasive pressure measurement. The goal was to see if the software's results matched the standard invasive test. If accurate, this could make diagnosing coronary artery disease faster and less risky.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
AutocathFFR software
What this could lead to
If successful, this software could provide a non-invasive way to diagnose significant coronary blockages, reducing the need for invasive procedures.
What could go wrong
This is a small, retrospective study that only compares software results to existing data. It may not work as well in real-time use or in all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

100 people

The number who actually took part.

Started

Aug 2023

Finished

Jan 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Retrospective analysis of coronary angiograms of 100 consecutive patients who have undergone fractional flow reserve (FFR) testing within our institution

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patients who are \>18 years of age, undergone a coronary angiogram for a clinically indicated reason, and who underwent coronary hemodynamic testing with invasive FFR. Exclusion Criteria: * Invasive FFR not obtained

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome Angina, Stable coronary artery disorder intermediate coronary syndrome Non-ST Elevated Myocardial Infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stable angina, unstable angina, nstemi

Contacts and locations

Locations

  • UC San Diego Health

    La Jolla, California, 92037, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.