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Prostate cancer detection may soon be as simple as a urine test

NCT ID NCT02657863

Diagnosis Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study collected blood and urine samples from 61 men with prostate cancer and healthy volunteers to look for cancer DNA. The goal is to develop a non-invasive way to detect and track prostate cancer without needing a biopsy. Researchers compared genetic material from cancer patients to healthy individuals to find differences that could lead to better diagnosis and treatment monitoring.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could lead to a simple, non-invasive test to detect and monitor prostate cancer using blood or urine samples.
What could go wrong
This is an early-stage observational study with only 61 participants, so results may not apply broadly. The approach is still experimental and may not prove reliable enough for clinical use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

61 people

The number who actually took part.

Started

Nov 2014

Finished

Apr 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Healthy volunteers and men with prostate cancer

Ages

18 to 100 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Male older than or equal to 18 years of age, but not older than 100 years of age. 2. Signed informed consent prior to initiation of any study-related procedures. 3. Minorities are included in this protocol. 4. Signed informed consent prior to initiation of any study-related Exclusion Criteria: 1. It is the enrolling study physician's discretion to decide if a patient is not fit enough to undergo procedures outlined in this protocol. 2. Persons who are incarcerated are not eligible to participate. 3. Women are not eligible. 4. Persons incapable of providing informed consent are not eligible. 5. Any person with a personal history of prior malignancy is not eligible 6. Persons with an inherited cancer syndrome or a medical history suggestive of an inherited cancer syndrome are not eligible.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Prostate cancer

Contacts and locations

Locations

  • Johns Hopkins SKCCC

    Baltimore, Maryland, 21287, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.