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Nighttime blood pressure pattern may reveal hidden heart risks

NCT ID NCT07200856

Knowledge-focused Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether the natural drop in blood pressure during sleep (called 'dipping') is linked to changes in the heart's electrical activity in people with high blood pressure. Researchers will monitor 140 adults using a 24-hour blood pressure device and compare those whose blood pressure dips enough at night to those whose does not. The goal is to see if a lack of nighttime dipping is tied to higher risk for dangerous heart rhythms, which could help doctors better assess heart risk in the future.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better identify hypertensive patients at higher risk for heart problems based on their nighttime blood pressure patterns.
What could go wrong
This is an observational study, not a treatment trial. It will not directly change patient care, and results may not apply to all patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 140 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2025

An estimate. Start dates often move.

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients (≥18 years) with essential hypertension attending the Cardiology Department at Assiut University Heart Hospital. All participants will undergo 24-hour ambulatory blood pressure monitoring, electrocardiography, and echocardiography to classify them into dipper and non-dipper groups

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults ≥18 years old * Diagnosed with essential hypertension * Completed 24-hour ambulatory blood pressure monitoring (ABPM) * Availability of good-quality 12-lead ECG * Availability of good-quality transthoracic echocardiography Exclusion Criteria: * Body mass index (BMI) \> 34.9 kg/m² * Atrial fibrillation or atrial flutter * Use of QT-prolonging medications * End-stage renal disease or liver failure * Bundle branch block or presence of pacemaker * Prior coronary revascularization (PCI or CABG) * Significant electrolyte imbalance

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Conditions

The condition(s) this trial relates to.

circadian rhythm sleep disorder essential hypertension hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Blood pressure monitoring, ambulatory Circadian rhythm Electrocardiography Hypertension Ventricular function

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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Other studies related to the condition(s) this trial covers.