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Gentler vein harvesting may keep bypass grafts open longer

NCT ID NCT03501303

Disease control Sponsor: Uppsala University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a 'no-touch' method for taking veins from the leg during heart bypass surgery, compared to the usual technique. Over 900 patients were followed for two years to see if the no-touch method kept the vein grafts open better. The goal is to improve long-term success of bypass surgery and reduce the need for additional procedures.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
No-touch vein harvesting technique (procedure)
What this could lead to
If successful, this technique could reduce the need for repeat procedures and improve long-term outcomes for heart bypass patients.
What could go wrong
This is a completed trial, but the benefit may be modest or not apply to all patients. Surgical technique changes can have variable results across centers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

902 people

The number who actually took part.

Started

Apr 2018

Finished

Nov 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Up to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * first time CABG patients * age up to 80 years at the time for inclusion * need for at least one vein graft * able to provide informed consent and accepted for isolated primary non-emergent CABG. Exclusion Criteria: * unable to use greater saphenous vein grafts (SVG) due to previous vein stripping or poor vein quality * allergy to contrast dye * renal failure with glomerular filtration rate (GFR)\<15 ml/min * coagulation disorders * excessive risk of wound infection * participation in other interventional trial on grafts * any condition that seriously increases the risk of non-compliance or loss of follow-up

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Conditions

The condition(s) this trial relates to.

myocardial ischemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ischemic heart disease

Contacts and locations

Locations

  • Aarhus

    Aarhus, Denmark

  • Göteborg

    Gothenburg, Sweden

  • Karlskrona

    Karlskrona, Sweden

  • Karolinska Sjukhuset

    Stockholm, Sweden

  • Linköping

    Linköping, Sweden

  • Lund

    Lund, Sweden

  • Umeå

    Umeå, Sweden

  • Uppsala

    Uppsala, Sweden

  • Örebro, Sweden

    Örebro, Sweden

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