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Shocking seniors stronger: new combo therapy tested

NCT ID NCT07646405

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether combining neuromuscular electrical stimulation (gentle electrical pulses to the calf muscles) with low-intensity resistance training (like seated leg presses with a resistance band) can improve muscle strength, muscle size, and physical endurance in adults aged 65 to 85. About 44 participants will be randomly assigned to either the combined therapy group or a control group. The goal is to find a safe, accessible way to combat age-related muscle weakness.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
neuromuscular electrical stimulation and low-intensity resistance training
What this could lead to
If it works, this could offer a simple, non-drug way for older adults to regain muscle strength and endurance.
What could go wrong
This is a small, early-stage trial with only 44 participants, so results may not apply to everyone. The exercises and stimulation may not work for all seniors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 44 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria:• Age: 65 to 85 (35) * Both male and female will be added(29) * Patients with low calf muscle mass \<31.5 cm for females and \<33.5 cm for males will be included in this study(36). * Participants able to complete the Five Times Sit-to-Stand Test in ≤ 10 seconds (men) or ≤ 11 seconds (women)(37). * Participants must have ability to walk independently and absence of severe medical conditions(29). * Participants who takes \> 12 seconds to complete TUG will be included in this study(38 Exclusion Criteria:• Participants with contraindications to NMES or RT, such as pacemakers or severe cardiovascular disease(29). * Participants with a MoCA score of less than 26 will be excluded to ensure adequate cognitive ability to comprehend and follow the study protocol, including exercise and neuromuscular stimulation procedures (39). * Participants with any musculoskeletal issues will be excluded from this study(35). * Participants with neuromuscular disorders that may affect muscle strength or function(29).

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Conditions

The condition(s) this trial relates to.

Frailty

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Study site

    RECRUITING

    Lahore, Punjab Province, 54000, Pakistan

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