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Could a gut bug boost kidney cancer treatment?

NCT ID NCT07128680

First seen Jan 31, 2026 · Last updated May 22, 2026 · Updated 13 times

Summary

This early-stage trial tests whether adding a live bacteria product (EXL01) to standard immunotherapy drugs (nivolumab and ipilimumab) is safe and helps control metastatic kidney cancer. About 33 adults with advanced kidney cancer that has spread will receive either the standard drugs alone or with EXL01. The goal is to see if changing gut bacteria can make the immune therapy work better.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope Medical Center

    NOT_YET_RECRUITING

    Irvine, California, 92618, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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