Glow-in-the-Dark tool may make parathyroid surgery safer and faster
NCT ID NCT05152927
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a device called PTeye that uses near-infrared light to help surgeons spot parathyroid glands during surgery for hyperparathyroidism. The goal was to see if it could reduce the number of tissue samples sent to the lab and lower the risk of needing a second surgery. The trial included 79 adults with primary hyperparathyroidism. The device is meant to make surgery more efficient and improve patient outcomes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- PTeye (Near Infrared Autofluorescence detection device)
- What this could lead to
- If successful, this device could make parathyroid surgery faster, reduce the need for tissue biopsies, and lower the chance of repeat surgeries.
- What could go wrong
- This is a small, completed study with 79 participants, so results may not apply to all patients. The device is a tool to assist surgeons, not a cure, and its benefits may vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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79 people
The number who actually took part.
- Started
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Jan 2022
- Finished
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Nov 2024
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All adults \>=18 years old) patients with primary hyperparathyroidism who will be undergoing parathyroid surgery * All adult (\>=18 years old) patients with persistent primary hyperparathyroidism after having undergone a failed prior parathyroid surgery who will be undergoing repeat parathyroid surgery Exclusion Criteria: * Children and minors * Pregnant women * Patients with concurrent parathyroid and thyroid disease that require total thyroidectomy * Patients with secondary or tertiary hyperparathyroidism
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of California, San Francisco
San Francisco, California, 94143, United States
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