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Herbal capsule could soothe hemorrhoid pain in just 10 days

NCT ID NCT07669662

Symptom relief Sponsor: Nimsai Academia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a daily herbal capsule called Nimsai Herbal can shrink hemorrhoids and reduce symptoms like pain and itching. Fifty adults with grade 2-3 hemorrhoids will take either the herbal blend or a placebo for 10 days. The main goal is to see if the hemorrhoids improve or if symptoms drop by at least 75%.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Nimsai Herbal (a blend of Centella asiatica extract, turmeric extract, and black pepper extract)
What this could lead to
If it works, this could offer a natural, short-term option to shrink hemorrhoids and ease symptoms like pain and bleeding.
What could go wrong
This is a small, early-phase trial with only 50 people over 10 days. The herbal blend may not work better than placebo, and long-term safety or effectiveness is unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Endoscopically confirmed Grade 2 or 3 internal hemorrhoids History of hemorrhoidal symptoms persisting for more than 6 weeks prior to screening Age 18 to 70 years inclusive at time of informed consent Willingness and ability to provide written informed consent Willingness and ability to comply with all study procedures, schedules, and follow-up requirements Exclusion Criteria: * Diagnosis of Grade 1 or Grade 4 hemorrhoids Any known anorectal malignancy or suspicion of malignancy Active bleeding from sources other than hemorrhoids Currently pregnant or lactating women, or women of childbearing potential not using effective contraception Known hypersensitivity or allergy to any component of Nimsai Herbal or placebo Significant systemic diseases including severe cardiovascular disease, severe renal impairment, severe hepatic dysfunction, or uncontrolled diabetes mellitus (HbA1c \> 9%) Any medical or psychiatric condition that might compromise participant safety or data integrity Participation in another interventional clinical trial within 30 days prior to screening Use of concurrent treatments for hemorrhoids within 7 days prior to screening History of hemorrhoidectomy or other invasive hemorrhoid procedures within the last 6 months

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Conditions

The condition(s) this trial relates to.

hemorrhoid internal hemorrhoid Varicose Ulcer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hemorrhoid Hemorrhoidal disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    1 site. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Nimsai Academia Clinical Research Center

    Bursa, Turkey (Türkiye)

    Contact Email: •••••@•••••

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