New study tests diet and exercise combo for colon cancer recovery
NCT ID NCT07534852
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a special nutritional supplement (HMB and vitamin D) combined with a structured exercise program can improve muscle strength and recovery in adults after colon cancer surgery. About 120 participants will be randomly assigned to different combinations of nutrition and physical activity. The goal is to learn how these interventions affect muscle mass, inflammation, and overall quality of life during the six-month recovery period.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 to 75 years. * Male and female participants. * Diagnosis of colon cancer at localized or locally advanced stages (TNM stages I-III). * Patients scheduled for primary surgical treatment. Exclusion Criteria: * Metastatic disease (stage IV) * Diagnosis of rectal cancer or tumors involving the rectum * Prior neoadjuvant chemotherapy or radiotherapy before surgery. * Presence of synchronous malignant tumors. * Pregnant or breastfeeding women. * Presence of severe medical conditions, including acute pancreatitis, severe liver or kidney disease, heart failure, severe pulmonary disease, or peripheral arterial disease affecting the lower limbs. * Diagnosis of anorexia nervosa or other severe eating disorders. * Known allergy or intolerance to any nutritional supplements used in the study. * Medical contraindications to moderate-to-vigorous physical activity. * Regular participation in high-intensity exercise programs. * High risk of poor adherence to the study procedures, as determined by the study team.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hospital Universitario Virgen de la Victoria
RECRUITINGMálaga, Malaga, 29010, Spain
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