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Could a Two-Drug combo help when standard cancer treatments fail?

NCT ID NCT02379416

First seen Mar 06, 2026 · Last updated May 24, 2026 · Updated 8 times

Summary

This early-phase trial tested whether adding nilotinib (a pill) to paclitaxel (an IV chemo drug) is safe for people with advanced solid tumors that have stopped responding to standard treatments. 47 adults and children aged 12 and older took part. The goal was to find the safest dose and see if the combination could help control the cancer. This is not a cure, but a way to possibly manage the disease when other options have run out.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.