Eye movements may reveal nicotine addiction in vapers
NCT ID NCT07604246
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to see how nicotine changes eye movements in people who use e-cigarettes. Researchers will measure things like how fast eyes move and how well they follow objects, along with blood nicotine levels and self-reported feelings. The goal is to find a more objective way to measure how addictive nicotine products are. The study will involve 25 daily e-cigarette users aged 21-50.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 25 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 21-50 years * Daily use of nicotine-containing electronic cigarettes for ≥ 6 months * Ability to abstain from nicotine for at least 12 hours prior to study visits * Fluent in English * Willingness to complete two in-person laboratory visits and all study procedures * Ability to provide informed consent Exclusion Criteria: * Use of combustible cigarettes or other tobacco/nicotine products on more than 5 of the past 30 days * Current enrollment in a nicotine cessation program or intent to quit in the next 30 days * Neurological conditions affecting eye movements (seizure disorder, movement disorders, head injury with loss of consciousness) * Normal or corrected-to-normal vision required; significant uncorrected visual impairment or ocular conditions affecting eye tracking * Cardiovascular conditions for which nicotine use is contraindicated, substance use disorder (other than nicotine), or current nicotine cessation treatment * Pregnancy or breastfeeding * Current medications affecting pupil size or eye movements (anticholinergics, stimulants, antipsychotics) * Any condition that, in the investigator's judgment, would interfere with safe participation * Age younger than 21 years or older than 50 years
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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Other studies related to the condition(s) this trial covers.
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