New devices could revolutionize cervical cancer screening in africa
NCT ID NCT05372484
First seen Jun 25, 2026 · Last updated Aug 11, 2026 · Updated 3 times
Summary
This study in Mozambique is testing two new technologies to improve cervical cancer screening and diagnosis. Researchers will compare a rapid HPV test and a special imaging device against standard methods in about 678 women. The goal is to find faster, more accurate ways to detect cervical cancer, especially in areas with limited resources.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to more accurate and accessible screening tools for cervical cancer in low-resource settings.
- What could go wrong
- This is an early-stage diagnostic study, not a treatment trial. The new technologies may not prove more accurate than current methods.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 678 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2021
- Expected to finish
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Mar 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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25 to 49 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. 25 - 49 year old women 2. Women with a positive cervical cancer screening test (abnormal cytology, positive VIA and/or positive HPV test) 3. Women with intact cervix 4. Women who are not pregnant and with a negative pregnancy test (within 14 days from the date of enrollment) ) and not currently breastfeeding 5. Willing and capable of providing informed consent Exclusion Criteria: 1. Women under 25 or over 49 years old 2. Women who have undergone a total hysterectomy (with removal of the cervix) 3. Women who are pregnant or breastfeeding
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
4 sites in 2 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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José Macamo General Hospital and Health Center
RECRUITINGMaputo, 1106, Mozambique
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M D Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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Maputo Central Hospital
RECRUITINGMaputo, 1106, Mozambique
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Mavalane Hospital and Health Center
RECRUITINGMaputo, 1108, Mozambique
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