New drug cocktail shows promise for myeloma patients ineligible for transplant
NCT ID NCT04009109
First seen Jan 03, 2026 · Last updated May 24, 2026 · Updated 22 times
Summary
This study tests a combination of four drugs (lenalidomide, ixazomib, dexamethasone, and daratumumab) in people newly diagnosed with multiple myeloma who cannot have a stem cell transplant. The goal is to see if adding two extra drugs to standard maintenance therapy helps keep the cancer from coming back longer. About 79 participants will receive the drug combo for 12 cycles, then be randomly assigned to one of two maintenance plans to compare effectiveness.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Gibbs Cancer Center & Research Institute/Spartanburg Regional Healthcare
Spartanburg, South Carolina, 29303, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Northern Light Eastern Maine Medical Center
Bangor, Maine, 04401, United States
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SUNY Upstate Medical Center
Syracuse, New York, 13210, United States
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University of Nebraska Medical Center
Omaha, Nebraska, 68152, United States
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University of North Carolina
Chapel Hill, North Carolina, 27514, United States
Conditions
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