Depression study probes hidden links between brain chemistry and gut bacteria
NCT ID NCT00285935
First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 26 times
Summary
This study looked at 228 adults with major depression and healthy volunteers to see if blood levels of natural brain compounds and genetic markers differ between the groups. Participants took a standard antidepressant for 8 weeks while researchers tracked mood, memory, and changes in the gut microbiome. The goal was to understand which biological differences improve with treatment, not to test a new cure.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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University of California San Francisco
San Francisco, California, 94143-0984, United States
Conditions
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