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Muscle relaxation depth may impact breathing after surgery

NCT ID NCT07464288

Knowledge-focused Sponsor: Ankara City Hospital Bilkent Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how deep muscle relaxation (using rocuronium) during abdominal surgery affects lung pressure and breathing problems after surgery. Researchers will compare deep versus moderate relaxation in 128 adults having open abdominal surgery. The goal is to see if one approach leads to fewer serious breathing issues like low oxygen or airway blockage.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Rocuronium
What this could lead to
If it works, this could help doctors choose the best muscle relaxation depth to reduce breathing problems after abdominal surgery.
What could go wrong
This is a small, early-stage study (128 people) that hasn't started yet. Results may not apply to all patients or surgeries, and the intervention is already in common use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 128 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Elective abdominal surgery under general anesthesia that is expected to last longer than one hour * ASA I-II-III * Age ≥18 years * Written informed consent Exclusion Criteria: * Refusal to participate in the study * ASA ≥ IV * Age \<18 * Obesity (BMI\>30) and cachexia (BMI \<18) * Laparoscopic surgery * Emergency procedure * Allergy to drugs used during induction and maintenance of general anesthesia * Presence of psychiatric/neurologic/neuromuscular disease * Risk of malignant hyperthermia or having any relative with history of malignant hyperthermia * Use of medications that may affect neuromuscular function (anticonvulsants, aminoglycosides, magnesium salts, etc.) * Pregnancy * Presence of advanced chronic lung disease (asthma, COPD, etc.) * Presence of advanced liver and renal disease (creatinine\>1.6, liver function tests above twice the normal range)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Driving pressure Neuromuscular blockade monitoring Postoperative respiratory complications

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ankara Bilkent City Hospital

    Ankara, Çankaya, 06530, Turkey (Türkiye)

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