Brain and body: new test may predict safe return to sport after knee injury
NCT ID NCT07659613
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at a new test called NEURO-K-STARTS for people who have had ACL knee surgery. The test combines standard jumping exercises with mental challenges to better mimic real sports situations. Researchers want to see if this combined approach gives a clearer picture of when it is safe to return to sports, compared to physical tests alone. The study involves 144 participants who are at least six months past their surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- NEURO-K-STARTS test battery
- What this could lead to
- If successful, this test could provide a more accurate way to decide when athletes are truly ready to return to sports after ACL surgery, potentially reducing re-injury risk.
- What could go wrong
- This is an early-stage observational study with no treatment being tested. The new test may not prove better than existing methods, and results may not apply to all athletes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 144 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Feb 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 35 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria (patients): * Patient who has undergone primary ACL reconstruction at least 6 months ago * Patient who has undergone an isokinetic strength test, the results of which do not indicate any contraindications to performing a functional test * Patient who has resumed performing horizontal jumps under the supervision of a healthcare professional * Patient with no history of surgery on the joints of the contralateral leg * Patient enrolled in or covered by a social security scheme * French-speaking patient who has signed an informed consent form Exclusion Criteria (patients): * Patient with a history of ligament surgery on the affected or contralateral knee * Patient with a BMI \< 18.5 or \> 30 * Patient who is professional athlete * Patient with severe associated conditions (neurological, connective tissue disorders, congenital diseases) * Patient with colour blindness * Patient with multi-ligament injury or associated osteotomy * Patient enrolled in another study whose procedures may interfere with this study * Protected patient: adults under guardianship, curatorship or other legal protection, or deprived of their liberty by judicial or administrative decision Inclusion Criteria (healthy volunteers): * Subject with no history of surgery on the joints of either leg * Subject who is member of or beneficiary of a social security scheme * French-speaking subject who has signed an informed consent form Exclusion Criteria (healthy volunteers): * Subject with a BMI \< 18.5 or \> 30 * Subject who is professional athlete * Subject with severe associated conditions (neurological, connective tissue disorders, congenital diseases) * Subject with colour blindness * Subject with multi-ligament deficiency or associated osteotomy * Subject enrolled in another study whose procedures may interfere with this study * Subject under legal protection: adults under guardianship, curatorship or other legal protection, or deprived of their liberty by judicial or administrative decision
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hôpital Privé Jean Mermoz
Lyon, 69008, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Which fixation method best heals a reconstructed ACL?
- Bone scaffold may help ACL grafts heal stronger
- Why some knees freeze after ACL surgery: scientists probe muscle inhibition
- Inside the knee: new navigation tech could make ACL surgery more precise
- Can a common Anti-Inflammatory replace opioids after ACL surgery?