Which injection spot works best for nerve pain in the lower back?
NCT ID NCT07372430
First seen Jun 27, 2026 · Last updated Jul 16, 2026 · Updated 2 times
Summary
This study tests two different injection locations for a nerve block to treat chronic low back and buttock pain caused by a trapped nerve. 54 adults with pain lasting over 3 months will receive an ultrasound-guided injection of numbing and anti-inflammatory medicine. The goal is to see which injection spot provides better pain relief and function over time.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine and dexamethasone injection
- What this could lead to
- If successful, this could identify a better injection technique to relieve chronic low back and buttock pain from nerve entrapment.
- What could go wrong
- This is a small, early-stage study (54 people) comparing two approaches, not a new treatment. Results may not apply to everyone, and pain relief may be temporary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 54 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will consist of adult patients aged 18 to 75 years presenting with chronic low back and/or gluteal pain lasting longer than three months, who are clinically suspected of having superior cluneal nerve entrapment based on physical examination findings. Eligible participants will be those who have not responded to conservative treatment and who attend the Algology Outpatient Clinic during the study period. Only patients with unilateral symptoms who meet all inclusion and exclusion criteria and who provide written informed consent will be included in the study.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age between 18 and 75 years * Chronic low back and/or gluteal pain lasting longer than 3 months * Localized point tenderness and/or paresthesia on palpation over the unilateral posterior iliac crest * Clinical suspicion of superior cluneal nerve entrapment based on physical examination * Failure to respond to conservative treatment * Ability and willingness to provide written informed consent Exclusion Criteria: * Active local or systemic infection * Cognitive impairment or psychiatric disorders interfering with study participation * History of malignancy or cancer-related pain * Uncontrolled diabetes mellitus or severe comorbid conditions adversely affecting general health * Pregnancy * Known allergy to the medications used in the injection * Prominent radicular pain associated with neurological deficit * History of interventional procedures applied to the lumbar region within the last 6 months * Initiation of another lumbar interventional or medical treatment during the follow-up period * Suspected bilateral superior cluneal nerve entrapment * Sphincter dysfunction related to neurological disease * Bleeding diathesis or coagulation disorders
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Health Sciences University Gaziosmanpaşa Physical Medicine and Rehabilitation Training and Research Hospita
RECRUITINGIstanbul, 34255, Turkey (Türkiye)