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New combo drug aims to stop chemo-induced vomiting in advanced breast cancer

NCT ID NCT07132749

ENROLLING_BY_INVITATION Symptom relief Sponsor: Yeon Hee Park Source: ClinicalTrials.gov ↗

First seen Jan 11, 2026 · Last updated May 22, 2026 · Updated 12 times

Summary

This study looks at whether a drug called NEPA (netupitant/palonosetron) can prevent nausea and vomiting in people with advanced HER2-positive or HER2-low breast cancer who are being treated with T-DXd. About 100 adults will take NEPA and be monitored for up to 504 hours after each dose. The goal is to see if they can avoid vomiting and needing rescue medication, especially during the long-delayed phase.

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Contacts and locations

Locations

  • Samsung Medical Center

    Seoul, Gangnam-gu, 06355, South Korea

Conditions

Explore the condition pages connected to this study.