New tooth putty could replace old chemical in Kids' cavity treatment
NCT ID NCT07437794
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new material called NeoPutty MTA against a standard chemical, formocresol, for treating deep cavities in children's back baby teeth. About 68 kids aged 4 to 9 will get one of the two treatments to save the tooth and prevent pain or infection. Researchers will check for pain, swelling, and tooth health over time to see which works better.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 68 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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May 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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4 to 9 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Children with asymptomatic decayed primary mandibular molar(s). * Patient and parent showing cooperation and compliance. * Children 4-9 years old. * Vital carious primary(s) with complete root formation. * Asymptomatic teeth or without clinical symptoms of spontaneous pain. * No clinical evidence of pulp degeneration like the history of spontaneous or nocturnal pain, tenderness to percussion, pathologic tooth mobility, swelling, or fistulous tract. * Both genders will be included. * No radiographic evidence of pulp degeneration such as internal root resorption, external root resorption, or furcal radiolucency. * Presence of two thirds of the root. * Teeth that can be restored. * Children with prior parental consent. Exclusion Criteria: * History of any systemic disease. * Hemostasis is not achieved within 5 minutes of pulp amputation, by direct contact with a wet cotton pellet before the material placement. * The remaining radicular tissue was non-vital (with suppuration or purulence necrosis).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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October university for modern sciences and arts
Giza, Giza Governorate, 12116, Egypt
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Other studies related to the condition(s) this trial covers.