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Immunotherapy duo shows promise against hard-to-treat colorectal cancer

NCT ID NCT07160647

First seen Oct 31, 2025 · Last updated May 22, 2026 · Updated 28 times

Summary

This study tests two immunotherapy drugs (iparomlimab and tuvonralimab) given before surgery to people with a specific genetic type of advanced colorectal cancer (MSI-H/dMMR). The goal is to see if this approach can eliminate all cancer cells before surgery and to learn more about which patients benefit most. About 29 adults with stage IIB-III rectal cancer that can be surgically removed will participate.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Sir Run Run Shaw Hospital, Zhejiang University School of Medicine,

    Hangzhou, Zhejiang, 310016, China

Conditions

Explore the condition pages connected to this study.