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New hope for lung cancer patients Who've run out of options?

NCT ID NCT07306624

First seen Jan 03, 2026 · Last updated Jun 23, 2026 · Updated 28 times

Summary

This phase 2 trial tests a new drug called nelmastobart combined with the chemotherapy docetaxel in 62 people with advanced non-small cell lung cancer that no longer responds to platinum chemo or immunotherapy. The goal is to see if the combination can slow cancer growth and improve survival. Participants must have a specific marker (BTN1A1 TPS score ≥50) to join.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Kangbuk Samsung Hospital

    RECRUITING

    Seoul, South Korea

    Contact

  • Korea University Anam Hospital

    NOT_YET_RECRUITING

    Seoul, South Korea

    Contact

  • Samsung Medical Center

    RECRUITING

    Seoul, South Korea

    Contact

  • Seoul National University Bundang Hospital

    NOT_YET_RECRUITING

    Seoul, South Korea

    Contact

  • The Catholic University of Korea St. Vincent's Hospital

    NOT_YET_RECRUITING

    Gyeonggi-do, South Korea

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nelmastobart and docetaxel

What this could lead to

If successful, this combination could offer a new treatment option for people with advanced lung cancer who have stopped responding to standard therapies.

What could go wrong

This is an early-phase trial with only 62 participants, so results may not apply to everyone. The combination may cause side effects and might not improve survival.

Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.