Poking skin to bring back color: which needle works best for vitiligo?
NCT ID NCT06991972
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests two ways of puncturing white patches of skin—using a single needle or a microneedling device—followed by UV light therapy to see which helps restore pigment better. Eighty adults with stable non-segmental vitiligo will receive six sessions over 24 weeks. The goal is to achieve at least 25% repigmentation with minimal side effects.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- needling or microneedling procedure plus narrowband UVB light therapy
- What this could lead to
- If successful, this could point toward a more effective skin-puncturing technique to restore pigment in stable vitiligo patches.
- What could go wrong
- This is a small, early-phase trial with only 80 participants. Results may not apply to all vitiligo types, and risks include scarring, infection, or uneven pigmentation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2025
- Expected to finish
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Aug 2025
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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15 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Both male and female * Age 15-60 years * Patients having vitiligo for more than 1 year Exclusion Criteria: * Patients with tendency of keloid formation or hypertrophic scarring * Patients with any bleeding disorder, coagulation defect or using anti platelets * Any local infection at the treatment site * Patients who had received systemic therapy in last 6 months
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Khyber Teaching Hospital
RECRUITINGPeshawar, Khyber Pakhtunkhwa, 25000, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a skin cream bring back color to faces with vitiligo?
- Skin markers may reveal how light therapy fights vitiligo
- Can Real-World data unlock better skin disease care?
- New ointment aims to restore skin color in vitiligo
- Skin microbes linked to vitiligo and immunotherapy reactions in melanoma patients