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Can a simple mist calm your heart during surgery?

NCT ID NCT07596004

Symptom relief Sponsor: Shaheed Mohtarma Benazir Bhutto Institue of Trauma Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests if a drug given as a mist before surgery can lessen the sudden rise in heart rate and blood pressure when a breathing tube is placed. About 66 adults having planned surgery will receive either the drug or a saltwater mist. The goal is to see if the drug makes the procedure safer and more comfortable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 66 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 18-60 years 2. Either gender 3. ASA Physical Status I and II 4. Mallampati airway class I and II 5. BMI 18-30 kg/m2 6. Patients undergoing elective surgery under general anesthesia Exclusion Criteria: 1. Patient refusal or lack of consent 2. Anticipated difficult airway 3. Intubation attempt lasting more than 15 seconds 4. Pregnancy 5. Uncontrolled hypertension, cardiac, pulmonary, hepatic, or cerebral events 6. Known allergy to dexmedetomidine or study drugs

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hemodynamic responseto lyrangoscopy and endotracheal intubation

Contacts and locations

Locations

  • SMBBIT

    Karachi, Sindh, 7500, Pakistan