New imaging tool reveals hidden heart attack triggers
NCT ID NCT00540761
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at fatty deposits called plaques that can build up in heart arteries and sometimes cause heart attacks. Researchers are using a new imaging method to find a specific type of dangerous plaque in 320 people with heart disease. The goal is to learn more about these plaques, not to treat them directly.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 320 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2007
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Undergoing PCTI for coronary artery disease * Women with childbearing potential must have a negative pregnancy test within the 7 days prior to study entry Exclusion Criteria: * Kidney insufficiency (i.e., GFR\<50ml/min) * OR pregnancy * OR participants who have had a ST elevation heart attack will be excluded for at least 72 hours post-heart attack and until cardiac enzymes return to normal. Participants who have had a non-ST elevation heart attack will be excluded if they have evidence of ongoing ischemia, defined as chest pain or new electrocardiogram (ECG) changes in the 12 hours prior to study entry and/or rising creatine kinase (CK) and CK-MB serum enzymes. * OR high-risk and complex lesions, including tortuous blood vessels and lesions with thrombosis * OR unprotected left main coronary artery disease * OR enrolled in another investigational clinical trial within the 6 months prior to study entry * OR severe peripheral vascular disease * OR active ischemia * OR congestive heart failure * OR prior coronary artery bypass surgery * OR emergent procedures * OR inability to return for study follow-up procedures
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Columbia Presbyterian Medical Center
New York, New York, 10032, United States
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Lahey Clinic
Burlington, Massachusetts, 01805, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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