New hope for rare skin emergency? tiny trial tests etanercept
NCT ID NCT02987257
First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 38 times
Summary
This study tested whether the drug etanercept can help people with severe skin reactions called Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Only 2 adults took part, receiving either etanercept or a placebo along with standard supportive care. The goal was to see how fast the skin healed and to collect samples for future research.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Emory University at Grady Memorial Hospital
Atlanta, Georgia, 30303, United States
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Johns Hopkins Bayview Medical Center
Baltimore, Maryland, 21224, United States
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Loyola University Medical Center
Maywood, Illinois, 60153, United States
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MedStar Washington Hospital Center
Washington D.C., District of Columbia, 20010, United States
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University of California, Davis Medical Center
Sacramento, California, 95817, United States
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University of Florida Health Burn Center
Gainesville, Florida, 32610, United States
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University of Miami, Ryder Trauma Center
Miami, Florida, 33136, United States
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University of Tennessee Health Sciences Center
Memphis, Tennessee, 38103, United States
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University of Texas Medical Branch
Galveston, Texas, 77555, United States
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University of Texas Southwestern Medical Center
Dallas, Texas, 75390, United States
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University of Washington, Harborview Medical Center
Seattle, Washington, 98104, United States
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Valleywise Health Medical Center
Phoenix, Arizona, 85008, United States
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Vanderblt University Medical Center
Nashville, Tennessee, 37232, United States
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Wayne State University
Detroit, Michigan, 48201, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
etanercept
What this could lead to
If it works, this could point toward a better treatment for severe skin reactions like Stevens-Johnson syndrome.
What could go wrong
This trial is very small (only 2 participants) and completed, so results may not apply to others. Etanercept may not speed healing or reduce risks.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.