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NASA tests blue light and meal timing to keep pilots sharp on Long-Haul flights

NCT ID NCT07761611

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 12, 2026 · Last updated Aug 26, 2026 · Updated 3 times

Summary

This NASA study tests two simple countermeasures—eating very little during the biological night and wearing blue-enriched light glasses after rest breaks—to see if they can reduce fatigue and improve alertness in airline pilots flying long-haul routes over eight hours. Researchers will track pilots' sleep, sleepiness, workload, and reaction times before, during, and after trips. The goal is to find practical ways to help pilots stay vigilant and perform safely on overnight flights.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Caloric restriction and blue-enriched light exposure
What this could lead to
If effective, these simple countermeasures could help airline pilots stay alert and perform better during long flights, potentially improving aviation safety.
What could go wrong
This is an early-stage study with a specific pilot population, so results may not apply to all shift workers. The interventions may be impractical or have limited effect in real-world conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 118 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Jul 2029

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All medically qualified, active-duty pilots currently flying overnight long-haul operations are eligible to be included as participants in the study. Participants must be line pilots that spend at least 50% of their typical monthly schedule flying long-haul operations (defined at flights over eight hours induration). Exclusion Criteria: * Pilots with metabolic disorders, such as diabetes, those actively trying to lose weight or receiving GLP-1 injections, or those who indicate that they are sensitive to light will be excluded from participation. The medical monitor will review the pilot's self-reported medical conditions and medications (if applicable) prior to enrolment in the study.

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Conditions

The condition(s) this trial relates to.

Fatigue

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • NASA Ames Research Center

    Mountain View, California, 94043, United States