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New hope for bile duct cancer: experimental drug enters final testing phase

NCT ID NCT07265674

First seen Dec 10, 2025 · Last updated May 21, 2026 · Updated 18 times

Summary

This study tests a new drug called nanvuranlat in 480 adults with advanced biliary tract cancer (bile duct cancer) that has already been treated. The goal is to see if nanvuranlat helps people live longer compared to standard treatments like chemotherapy or best supportive care. Participants receive treatment every two weeks until their cancer worsens or side effects become unacceptable.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Allegheny Health Network (Site 121)

    NOT_YET_RECRUITING

    Pittsburgh, Pennsylvania, 15212, United States

  • City of Hope (Site 107)

    RECRUITING

    Duarte, California, 91010, United States

  • City of Hope - Chicago Cancer Center (Site 128)

    RECRUITING

    Zion, Illinois, 60099, United States

  • Comprehensive Cancer Centers of Nevada - Central Valley (Site 124)

    RECRUITING

    Las Vegas, Nevada, 89169, United States

  • Fred Hutchinson Cancer Center Clinic (Site 122)

    NOT_YET_RECRUITING

    Seattle, Washington, 98109, United States

  • James Cancer Hospital and Solove Research Institute (Site 119)

    NOT_YET_RECRUITING

    Columbus, Ohio, 43219, United States

  • Karmanos Cancer Center (Site 109)

    NOT_YET_RECRUITING

    Detroit, Michigan, 48201, United States

  • Masonic Cancer Center, University of Minnesota (Site 116)

    NOT_YET_RECRUITING

    Minneapolis, Minnesota, 55455, United States

  • Memorial Sloan Kettering Cancer Center (Site 108)

    NOT_YET_RECRUITING

    New York, New York, 10065, United States

  • Mercy Clinic (Site 110)

    RECRUITING

    Oklahoma City, Oklahoma, 73120, United States

  • Moffitt Cancer Center Magnolia Campus (Site 123)

    NOT_YET_RECRUITING

    Tampa, Florida, 33612, United States

  • Mount Sinai Comprehensive Cancer Center (Site 125)

    NOT_YET_RECRUITING

    Miami Beach, Florida, 33140, United States

  • Norton Cancer Institute (Site 115)

    NOT_YET_RECRUITING

    Louisville, Kentucky, 40127, United States

  • Ochsner Medical Center (Site 120)

    NOT_YET_RECRUITING

    New Orleans, Louisiana, 70121, United States

  • Oregan Health and Science University (Site 127)

    NOT_YET_RECRUITING

    Portland, Oregon, 97210, United States

  • Rosewell Park Comprehensive Cancer Center (Site 114)

    NOT_YET_RECRUITING

    Buffalo, New York, 14263, United States

  • Rutgers Cancer Institute of New Jersey (Site 103)

    RECRUITING

    New Brunswick, New Jersey, 08901, United States

  • UCLA Medical Center (Site 117)

    NOT_YET_RECRUITING

    Santa Monica, California, 90404, United States

  • University Hospitals Cleveland Medical Center Seidman Cancer Center (Site 111)

    RECRUITING

    Cleveland, Ohio, 44106, United States

  • University of California at Irvine (Site 101)

    RECRUITING

    Orange, California, 92868, United States

  • University of Iowa Hospitals and Clinics (Site 126)

    NOT_YET_RECRUITING

    Iowa City, Iowa, 54242, United States

  • University of Texas MD Anderson Cancer Center (Site 102)

    NOT_YET_RECRUITING

    Hosuton, Texas, 77030, United States

  • University of Texas Southwestern Medical Center (Site 104)

    RECRUITING

    Dallas, Texas, 75390, United States

Conditions

Explore the condition pages connected to this study.