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Could coated brackets make braces move teeth faster?

NCT ID NCT07818590

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 14, 2026 · Last updated Sep 16, 2026 · Updated 2 times

Summary

Orthodontic treatment can take a long time, partly because friction between brackets and wires slows tooth movement. Researchers at Cairo University are testing whether coating brackets with nanoparticles reduces that friction and speeds up canine retraction. The trial enrolls 28 people aged 13 to 30 who need two upper first premolars removed and their canine teeth pulled back. Each participant receives a nanoparticle-coated bracket on one side and a standard bracket on the other, and researchers track tooth movement with digital models taken every month for three months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
nanoparticle-coated orthodontic brackets
What this could lead to
If it works, nanoparticle-coated brackets could shorten orthodontic treatment time and reduce the discomfort and risks that come with long treatment.
What could go wrong
This is a small, single-center study of 28 people, so the results may not hold up in larger or more varied groups. Laboratory findings do not always translate to real-world orthodontic settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

28 people

The number who actually took part.

Started

Oct 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

13 to 30 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients aged 13 to 30 years. 2. Treatment plan requiring extraction of both upper first premolars. 3. Anterior teeth protrusion necessitating canine retraction. 4. No previous orthodontic treatment. 5. No systemic diseases. 6. Not taking routinely used drugs. 7. Good oral hygiene. 8. No extractions required other than the specified upper first premolars. Exclusion Criteria: 1. Poor oral hygiene. 2. Previous orthodontic treatment. 3. Patients with active periodontal disease. 4. Presence of any craniofacial syndromes.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

To compare the effect of nanoparticle coated orthodontic brackets versus standard ones on the rate of canine retraction

Contacts and locations

Locations

  • Ahmed Mohamed Ebrahim Zarzora

    Giza, 12573, Egypt

  • Ahmed Mohamed Ebrahim Zarzora

    Giza, Egypt