New hope for faster surgery recovery: drug may cut Wake-Up time

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age is greater than or equal to 18 years old and less than 65 years old 2. Patients who need tracheal intubation under general anesthesia at the right time for orthopedics, urology, and thoracic elective surgery 3. Patients with American Society of Anesthesia physical status I or II 4. BMI≥18kg/m2, and ≤30kg/m2 5. The estimated anesthesia time is 1-4 hours. 6. The intraoperative narcotic analgesics (Sufentanil and Remifentanil) 7. The patient uses electronic intravenous analgesia pump after surgery 8. The patient has informed consent Exclusion Criteria: 1. patients who refused to participate in the study 2. pantients who refuse intravenous analgesia 3. medical history or family history of cognitive disorders,delirium, epilepsy, abalienation, anxiety or depression; 4. recent use of anticholinergic drugs, antidepressants, antianxietics or anticonvulsants 5. medical history of organic brain diseases or cranial vascular diseases 6. patients with a history of allergy to any drug used in the study 7. History of drug addiction and alcoholic intemperance or drug abuse 8. The patient is diagnosed with severe heart and lung disease, or active heart disease, or severe hepatic dysfunction (ChildePugh class C), or severe renal dysfunction (undergoing dialysis before surgery) ,critical illness (preoperative ASA physical status classification \> =3) 9. Participate in other clinical trials within 4 weeks 10. Patients who, during surgery, presented complications （cerebrovascular accidents、heart failure、pneumothorax）or transfer to the intensive care unit during hospitalization, and patients who chose to abandon. 11. Inability to communicate in the preoperative period because of coma, profound dementia, language barrier, or incapacity from severe disease 12. Anesthesia time is \<1 hour or \>4 hours 13. Patients had chronic pain (unsatisfied pain control for at least 1 month).