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Could a common supplement ease harmful behaviors in rare genetic disorder?

NCT ID NCT04381897

First seen Oct 31, 2025 · Last updated May 01, 2026 · Updated 28 times

Summary

This small pilot study tests whether N-acetylcysteine (NAC), a supplement that reduces oxidative stress, can lessen repetitive and self-injurious behaviors in people with Cornelia de Lange Syndrome (CdLS). Ten participants aged 13 to 35 will receive both NAC and a placebo at different times to see if NAC leads to meaningful improvements. The goal is to find a safer way to manage these challenging behaviors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins University School of Medicine

    Baltimore, Maryland, 21205, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.