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Parkinson's drug side effect trial halted early

NCT ID NCT03146130

First seen Jun 14, 2026 · Last updated Jun 23, 2026 · Updated 1 time

Summary

This study tested whether N-acetylcysteine (NAC), a common supplement, could help with impulse control disorders caused by Parkinson's medications. The trial planned to include 14 people with mild-to-moderate symptoms, but it was terminated early. Because it stopped before completion, we cannot draw reliable conclusions about NAC's effectiveness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHU Amiens Picardie

    Amiens, Picardie, 80054, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

N-acetylcysteine (NAC)

What this could lead to

If it worked, NAC could offer a way to reduce impulse control problems in people with Parkinson's without changing their main medications.

What could go wrong

The trial was terminated early and only enrolled 14 people, so results are very limited. It is unclear if NAC is effective or safe for this use.

Conditions

The condition(s) this trial relates to.

Disruptive, Impulse Control, and Conduct Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.