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Can massage and exercise beat back pain? new study aims to find out

NCT ID NCT07362420

Symptom relief Sponsor: National Yang Ming Chiao Tung University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether hands-on pressure to painful muscle spots (trigger point therapy) and a guided exercise program, alone or together, can reduce pain and improve daily function in adults with nonspecific low back pain. About 105 participants will be randomly assigned to one of three groups: trigger point therapy only, exercise only, or both. Treatments happen twice a week for four weeks, with assessments before, after the first session, and after the final session.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
myofascial trigger point manual compression and myofascial chain-based exercise
What this could lead to
If successful, this could point toward better noninvasive treatment options for people with nonspecific low back pain, potentially reducing pain and improving daily function.
What could go wrong
This is a small, early-stage trial with only 105 participants, so results may not apply to everyone. The treatments are noninvasive and low-risk, but the study may not find a clear benefit over standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 105 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 65 years * Nonspecific low back pain lasting longer than 6 weeks * Average low back pain intensity of 3 or higher on a 0-10 Numeric Pain Rating Scale * Presence of at least 6 myofascial trigger points identified across bilateral target muscles * Presence of muscle function impairments in at least 6 muscle groups based on functional muscle testing * Able to understand study procedures and participate in an exercise-based intervention * Willing and able to attend treatment sessions and complete study assessments Exclusion Criteria: * Currently pregnant * Diagnosed spondylolisthesis or vertebral compression fracture * Known malignancy or history of cancer affecting the spine * Previous lumbar spine surgery * Known neurological, infectious, or systemic disease that may affect pain or movement * Any other medical condition that, in the opinion of the investigators, would interfere with safe participation in the study

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Conditions

The condition(s) this trial relates to.

Low Back Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Non-specific low back pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • National Yang Ming Chiao Tung University

    Taipei, Taipei City, 112304, Taiwan

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