Music's hidden power: could a playlist soothe nerves before surgery?
NCT ID NCT06929208
First seen Aug 07, 2026 · Last updated Aug 07, 2026
Summary
This study looks at whether listening to music before a medical procedure can influence heart rate variability (HRV), a measure of the heart's ability to adapt to stress, and whether it relates to anxiety and depression. About 120 adults scheduled for procedures at three hospitals in Singapore will have their heart activity recorded before, during, and after music listening, along with questionnaires about their mood. The goal is to understand if music might be a simple way to ease pre-procedure stress.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Music listening
- What this could lead to
- If music is shown to improve heart rate variability and reduce anxiety before procedures, it could become a simple, drug-free way to help patients feel calmer and potentially improve outcomes.
- What could go wrong
- This is a small pilot study, so results may not apply to everyone. The link between heart rate variability and mood is complex, and music may not have a clear effect in all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2025
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. America Society of Anaesthesiologist (ASA) 1 to 3 adults undergoing procedures (surgery, pain procedures); 2. Able to read and understand English and/or Chinese; 3. Not receiving opioid prior to the procedures. Exclusion Criteria: 1. With chronic pain; 2. Opioid and drug abuse; 3. Scheduled postoperative Intensive care unit (ICU) admission; 4. With baseline non-sinus heart rhythm or on pacemaker support.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
3 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Changi General Hospital
NOT_YET_RECRUITINGSingapore, Singapore
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KK Women's and Children's Hospital
RECRUITINGSingapore, Singapore
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Singapore General Hospital
NOT_YET_RECRUITINGSingapore, Singapore
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