AI scans could help surgeons avoid overdosing muscle relaxants
NCT ID NCT07478120
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study of 31 gynecological surgery patients tested whether AI analysis of preoperative CT scans could predict the correct dose of muscle relaxant (neuromuscular blocking agent). The idea is that people with more muscle mass need a higher dose, but current dosing based on body weight can be inaccurate. Researchers used deep learning to measure muscle and fat from CT images and compared those measurements to the drug dose needed during surgery. The goal is to make anesthesia safer and more personalized.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors personalize anesthesia dosing based on a patient's actual muscle mass, reducing risks of under- or over-medication.
- What could go wrong
- This is a small, completed observational study (31 people) that only looked at one type of surgery. The findings may not apply to other surgeries or patients, and the AI method needs more testing before it can be used in routine care.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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31 people
The number who actually took part.
- Started
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Jan 2021
- Finished
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Mar 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients scheduled for elective gynecologic surgery under general anesthesia
- Ages
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19 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * American Society of Anesthesiologists physical class (ASA class) 1-3 * Patients scheduled for elective gynecologic surgery under general anesthesia * Patients undergoing abdominal computed tomography for routine preoperative preparation Exclusion Criteria: * Pregnant women * Decreased renal function (GFR\<60mL/min/1.73m2). * Patients taking drugs that affect deep neuromuscular blockade * Patients with a history of neuromuscular and muscle disorders
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Seoul National University Bundang Hospital
Gyeonggi-do, Sungnamsi, 13620, South Korea
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