New quadruple therapy aims to extend remission in multiple myeloma
NCT ID NCT03710603
First seen Feb 17, 2026 · Last updated May 01, 2026 · Updated 10 times
Summary
This phase 3 study tests whether adding daratumumab to a standard three-drug regimen (VRd) helps people with newly diagnosed multiple myeloma live longer without their cancer worsening. About 709 participants aged 18–70 who are eligible for high-dose therapy will receive either the four-drug combination or the standard three drugs. The main goal is to see if the new combo improves progression-free survival.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Alfred Hospital
Melbourne, Australia
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Ankara University
Ankara, Turkey (Türkiye)
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Azienda Ospedaliero-Universitaria Ospedali Riuniti Umberto I - G.M. Lancisi - G. Salesi Di Ancona
Ancona, Italy
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CHRU Hôtel Dieu
Nantes, France
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Erasmus MC
Rotterdam, Netherlands
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Hospital Clinic I Provincial de Barcelona
Barcelona, Spain
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Kantonsspital St. Gallen
Sankt Gallen, Switzerland
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Odense University Hospital
Odense, Denmark
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Oslo University Hospital
Oslo, Norway
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Regional General Hospital Alexandra
Athens, Greece
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University Hospital Leuven
Leuven, Belgium
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University Hospital Ostrava
Ostrava, Czechia
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Uniwersytet Jagiellonski Collegium Medicum
Krakow, Poland
Conditions
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