Real-World study tracks patient adherence to multiple myeloma drug regimens
NCT ID NCT02970747
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how faithfully adults with multiple myeloma (a type of blood cancer) follow their prescribed carfilzomib combination treatments in everyday medical practice. It included 359 patients who had already tried at least one prior therapy. The goal was to measure adherence and persistence to the drug regimen, not to test new treatments or compare effectiveness.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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359 people
The number who actually took part.
- Started
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Oct 2016
- Finished
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Apr 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients with multiple myeloma (MM) who have received at least one prior therapy
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 18 years or older. * Patients with MM who have received at least one prior therapy. * Indication for treatment as assessed by the treating physician. * Decision for second- or subsequent-line treatment with the combination therapy carfilzomib/ lenalidomide/ dexamethasone or carfilzomib/ dexamethasone or carfilzomib/ dexamethasone/ daratumumab * Signed written informed consent. * Criteria according to the current Summary of Product Characteristics (SmPC) for Kyprolis® (Carfilzomib) Exclusion Criteria: * Contraindications according to the current SmPC for Kyprolis® (Carfilzomib)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centrum für Hämatologie und Onkologie Bethanien
Frankfurt, 60389, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can engineered immune cells tackle resistant blood cancers?
- Can a new triple therapy outsmart resistant myeloma?
- Can a new immune cell therapy outsmart resistant blood cancers?
- Can a Triple-Drug cocktail tame resistant myeloma?
- Can a single gene therapy turn the body into a Cancer-Fighting factory?