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New drug aims to soften skin in rare autoimmune disease

NCT ID NCT05198557

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 29 times

Summary

This study tests an experimental drug called MT-0551 against a placebo in 80 adults with systemic sclerosis, a disease that causes skin thickening and can affect internal organs. The main goal is to see if the drug reduces skin hardening over 26 weeks. Researchers will also check safety and lung function changes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Kanazawa University Hospital

    Kanazawa, Ishikawa-ken, 920-8641, Japan

  • St. Marianna University Hospital

    Kawasaki-shi, Kanagawa, 216-8511, Japan

  • The University of Tokyo Hospital

    Bunkyo-ku, Tokyo, 113-8655, Japan

  • University of Fukui Hospital

    Yoshida-gun, Fukui, 910-1193, Japan

Conditions

Explore the condition pages connected to this study.