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Can measuring pelvic muscle function unlock the mystery of chronic pelvic pain?

NCT ID NCT05750212

Knowledge-focused Sponsor: Loyola University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time

Summary

This study compares pelvic muscle and nerve function in women with chronic pelvic pain to those without it. Researchers will measure muscle tone, tenderness, contraction, relaxation, and electrical activity. The goal is to understand how these functions differ, which may lead to better treatments in the future.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Diagnostic tests measuring pelvic floor muscle tone, tenderness, contraction, relaxation, and electrical activity
What this could lead to
If this study succeeds, it could point toward better ways to diagnose and treat chronic pelvic pain by clarifying how muscle and nerve function differ in affected women.
What could go wrong
This is an observational study, so it cannot prove cause and effect. The findings may not apply to all women with pelvic pain, and the measurements may not capture the full complexity of the condition.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

98 people

The number who actually took part.

Started

Jan 2023

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants are selected from a tertiary medical care center

Ages

21 to 80 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female sex * Age 21 to 80 years * Symptoms of CPP as defined by the American College of Obstetrics \& Gynecology (ACOG) for more than 6 months * At least two of seven overlapping CPP diagnosis (i.e., IC/PBS, IBS, Endometriosis, Vulvodynia, PN, FM, PFMP) * An average CPP pain score of at least three on a 10 point pain scale Exclusion Criteria: * Current or history of GI or GU pelvic cancer * Current pelvic infection (e.g., a UTI or vaginal infection) * Current or imminent planned pregnancy or recent delivery in the last 6 months * Abdominal or pelvic surgery in the last 36 months.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic pelvic pain syndrome

Contacts and locations

Locations

  • Loyola Medical Center

    Maywood, Illinois, 60153, United States

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