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MS drug trial halted after initial safety check

NCT ID NCT05798520

Completed Disease control Sponsor: Biogen Source: ClinicalTrials.gov ↗

Summary

This study tested a new oral drug, BIIB091, for people with relapsing forms of multiple sclerosis (MS). In the first part, 127 participants took either BIIB091 or an approved MS drug (diroximel fumarate) to check safety. The goal was to see if BIIB091, alone or combined with the other drug, could reduce new areas of inflammation in the brain seen on MRI scans. The sponsor decided not to proceed with the second, larger part of the trial.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • 'MHAT Avis - Medica' OOD

    Pleven, 5800, Bulgaria

  • Acibadem City Clinic Tokuda University Hospital Ead

    Sofia, 1407, Bulgaria

  • Alta Bates Summit Medical Center

    Berkeley, California, 94705, United States

  • Azienda Ospedaliera Universitaria Policlinico Tor Vergata

    Roma, 00133, Italy

  • Azienda Ospedaliera Universitaria Policlinico Umberto I - Università di Roma La Sapienza

    Roma, 00161, Italy

  • Azienda Ospedaliera Universitaria- Università degli Studi della Campania "Luigi Vanvitelli"

    Naples, 80138, Italy

  • COPERNICUS Podmiot Leczniczy Sp. z o. o.,

    Gdansk, 80-803, Poland

  • Caribbean Center for Clinical Research

    Guaynabo, San Juan, 00968, Puerto Rico

  • Centrum Medyczne Pratia Katowice

    Katowice, 40-081, Poland

  • Centrum Neurologii K. Selmaj

    Lodz, 90-324, Poland

  • DCC Neoclinic EAD

    Sofia, 1408, Bulgaria

  • Diagnostic Consultation Center CONVEX EOOD

    Sofia, 1680, Bulgaria

  • Fakultni Thomayerova nemocnice

    Praha 4-Krc, 14059, Czechia

  • Fakultni nemocnice Hradec Kralove

    Hradec Králové, 50005, Czechia

  • Fakultni nemocnice u sv. Anny v Brne

    Brno, 65691, Czechia

  • Fondazione Istituto G.Giglio di Cefalù

    Cefalù, Palermo, 90015, Italy

  • Fondazione Istituto Neurologico Casimiro Mondino

    Pavia, 27100, Italy

  • Fort Wayne Neurological Center

    Fort Wayne, Indiana, 46804, United States

  • Holy Name

    Teaneck, New Jersey, 07666, United States

  • HonorHealth Neurology

    Scottsdale, Arizona, 85251, United States

  • Hospital Regional Universitario de Malaga

    Málaga, 29010, Spain

  • Hospital Universitario Quironsalud Madrid

    Pozuelo de Alarcón, Madrid, 28223, Spain

  • Hospital Universitario Ramon y Cajal

    Madrid, 28034, Spain

  • Hospital Universitario Reina Sofia

    Córdoba, 14011, Spain

  • Hospital Universitario Virgen de la Arrixaca

    El Palmar, Murcia, 30120, Spain

  • Hospital del Mar

    Barcelona, 08003, Spain

  • I.R.C.C.S. Neuromed-Istituto Neurologico Mediterraneo

    Pozzilli, Isernia, 86077, Italy

  • IRCCS Ospedale Policlinico San Martino

    Genova, 16132, Italy

  • Inselspital - Universitaetsspital Bern

    Bern, 3010, Switzerland

  • Instytut Zdrowia dr Boczarska-Jedynak sp.z.o.o, Sp.K

    Oświęcim, 32-600, Poland

  • International Neurorehabilitation Institute

    Lutherville, Maryland, 21093, United States

  • Klinikum Bayreuth GmbH- Hohe Warte

    Bayreuth, Bavaria, 95445, Germany

  • Krajska zdravotni a.s. - Nemocnice Teplice o.z.

    Teplice, 41529, Czechia

  • M.A. - LEK A.M.Maciejowscy SC.

    Katowice, 40-571, Poland

  • MHATNP 'Sv.Naum', EAD

    Sofia, 1113, Bulgaria

  • Med-Polonia Sp. z o.o.

    Poznan, 60-693, Poland

  • NZOZ 'NEURO-KARD', 'Ilkowski i Partnerzy' Sp. Partn. Lek.

    Poznan, 61-853, Poland

  • Nemocnice Jihlava p.o.

    Jihlava, 58633, Czechia

  • NeuroProtect Sp. z o.o.

    Warsaw, 01-684, Poland

  • Neurology Clinic, PC

    Cordova, Tennessee, 38018, United States

  • Neuropraxis Muenchen Sued

    Unterhaching, Bavaria, 82008, Germany

  • Nzoz Novo-Med

    Katowice, 40-650, Poland

  • Nzoz Palomed

    Rzeszów, 35-323, Poland

  • Ospedale Regionale di Lugano

    Lugano, Canton Ticino, 6903, Switzerland

  • Resmedica Sp.z o.o

    Kielce, 25-726, Poland

  • S.C Clubul Sanatatii SRL

    Campulung Muscel, 115100, Romania

  • S.C Neurocity S.R.L

    Bucharest, 11302, Romania

  • Samodzielny Publiczny Specjalistyczny Szpital Zachodni im. Jana Pawla II

    Grodzisk Mazowiecki, 05-825, Poland

  • South Shore Neurologic Associates, P.C.

    Patchogue, New York, 11772, United States

  • Spitalul Universitar de Urgenta Elias

    Bucharest, 11461, Romania

  • Studienzentrum fur Neurologie und Psychiatrie

    Böblingen, Baden-Wurttemberg, 71034, Germany

  • Szpital Uniwersytecki w Krakowie

    Krakow, 31-503, Poland

  • The Boster Center for Multiple Sclerosis

    Columbus, Ohio, 43235, United States

  • The Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States

  • The Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • The University of Texas Health Science Center San Antonio

    San Antonio, Texas, 78229-3900, United States

  • UMHAT "Sv. Ivan Rilski", EAD

    Sofia, 1431, Bulgaria

  • UMHAT 'Dr. Georgi Stranski', EAD

    Pleven, 5800, Bulgaria

  • UMHAT 'Sv. Georgi', EAD

    Plovdiv, 4002, Bulgaria

  • Universitaetsklinikum Carl Gustav Carus TU Dresden

    Dresden, 01307, Germany

  • Universitaetsklinikum Duesseldorf AoeR

    Düsseldorf, North Rhine-Westphalia, 40225, Germany

  • Universitaetsspital Zuerich

    Zurich, 8091, Switzerland

  • University First MHAT-Sofia, 'St. Joan Krastitel' EAD

    Sofia, 1142, Bulgaria

  • University of California at Irvine Medical Center

    Orange, California, 92868, United States

  • University of Cincinnati Physicians Company

    Cincinnati, Ohio, 45267, United States

  • University of Colorado School of Medic

    Aurora, Colorado, 80045, United States

  • University of Kansas Medical Center Research Institute, Inc.

    Kansas City, Kansas, 66160, United States

  • University of Miami Miller School of Medicine

    Miami, Florida, 33136, United States

  • University of New Mexico

    Albuquerque, New Mexico, 87131-0001, United States

  • University of South Florida

    Tampa, Florida, 33612, United States

  • University of Wisconsin Hospital and Clinics

    Madison, Wisconsin, 53792, United States

  • Vanderbilt MS Center

    Nashville, Tennessee, 37215, United States

  • Vero Beach Neurology and Research Institute

    Vero Beach, Florida, 32960, United States

  • Wake Forest University - School of Medicine - Central

    Winston-Salem, North Carolina, 27157, United States

  • Washington University

    St Louis, Missouri, 63110, United States

  • Wielospecjalistyczne Centrum Medyczne Ibismed

    Zabrze, 41-800, Poland

  • ZNS - Zentrum fuer Neurologisch-Psychiatrische Studien

    Siegen, North Rhine-Westphalia, 57076, Germany

Conditions

Explore the condition pages connected to this study.

RELAPSING FORMS OF MULTIPLE SCLEROSIS