MS pill challenge: can a new oral drug match powerful injections?

NCT ID NCT06846281

Recruiting now Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study is for people with relapsing multiple sclerosis (MS) who are currently receiving ocrelizumab injections. It aims to see if switching to a new oral medication called remibrutinib is as effective and safe as continuing the ocrelizumab injections. About 360 participants will be randomly assigned to either switch to the pill or stay on their current injections, and researchers will monitor their MS activity and safety for up to 4 years.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Aqualane Clinical Research
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Naples, Florida, 34105, United States

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Austin Regional Clinic
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Austin, Texas, 78731, United States

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Center for Neurological Disorders G
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Greenfield, Wisconsin, 53228-1321, United States

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Holy Name Medical Center
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Teaneck, New Jersey, 07666, United States

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John Peter Smith Hospital
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Fort Worth, Texas, 76104, United States

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Lahey Hospital and Medical Center
RECRUITING

Burlington, Massachusetts, 01805, United States

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MedStar Montgomery Medical Center
RECRUITING

Olney, Maryland, 20832, United States

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Medstar Washington Hospital Center
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Washington D.C., District of Columbia, 20010-2975, United States

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Memorial HC Ins for Neuroscience
RECRUITING

Owosso, Michigan, 48867, United States

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Michigan Institute of Neurological
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Farmington Hills, Michigan, 48334, United States

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Neurology Associates PA
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Maitland, Florida, 32751, United States

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Neurology Center of New England PC
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Foxborough, Massachusetts, 02035, United States

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Neurology of Central FL Res Ctr
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Altamonte Springs, Florida, 32714, United States

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Novartis Investigative Site
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Rosario, Santa Fe Province, 2000, Argentina
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Rosario, Santa Fe Province, S2000BZL, Argentina
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Buenos Aires, C1012AAR, Argentina
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Buenos Aires, C1055AAF, Argentina
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Melbourne, Victoria, 3004, Australia
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Parkville, Victoria, 3050, Australia
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Liverpool, 2170, Australia
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St Leonards, 2065, Australia
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Bruges, 8000, Belgium
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Vancouver, British Columbia, V6T 2A1, Canada
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Lévis, Quebec, G6W 0M5, Canada
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Montreal, Quebec, H4A 3T2, Canada
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Aarhus N, 8200, Denmark
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Glostrup Municipality, 2600, Denmark
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Bordeaux, 33076, France
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Clermont-Ferrand, 63003, France
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Lille, 59000, France
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Marseille, 13885, France
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Nice, 06001, France
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Nîmes, 30029, France
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Paris, 75940, France
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Poitiers, 86021, France
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Strasbourg, 67000, France
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Toulouse, 31059, France
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Tours, 37044, France
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Chaïdári, 124 62, Greece
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Larissa, 411 10, Greece
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Thessaloniki, 53246, Greece
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Bergamo, BG, 24127, Italy
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Foggia, FG, 71122, Italy
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Genova, GE, 16132, Italy
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Milan, MI, 20132, Italy
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Pavia, PV, 27100, Italy
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Roma, RM, 00133, Italy
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Roma, RM, 00168, Italy
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Mexico City, Mexico City, 06700, Mexico
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Mexico City, 14050, Mexico
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Braga, 4710243, Portugal
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Coimbra, 3004-561, Portugal
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Lisbon, 1169-050, Portugal
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Bratislava, 826 06, Slovakia
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Trnava, 917 02, Slovakia
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Cape Town, Western Cape, 7405, South Africa
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Pretoria, 0041, South Africa
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Majadahonda, Madrid, 28222, Spain
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El Palmar, Murcia, 30120, Spain
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Valencia, Valencia, 46017, Spain
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Barcelona, 08035, Spain
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Córdoba, 14004, Spain
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Madrid, 28009, Spain
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Madrid, 28034, Spain
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Madrid, 28040, Spain
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Málaga, 29010, Spain
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Seville, 41009, Spain
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Valencia, 46026, Spain
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Bern, 3010, Switzerland
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Lausanne, 1011, Switzerland
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Zurich, 8091, Switzerland
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Sheffield, South Yorkshire, S10 2JF, United Kingdom
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Leeds, LS1 3EX, United Kingdom
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Swansea, SA6 6NL, United Kingdom
Ohio Health Research Institute
RECRUITING

Columbus, Ohio, 43214, United States

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Orlando Health Clinical Trials
RECRUITING

Orlando, Florida, 32806, United States

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Perseverance Research Center
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Scottsdale, Arizona, 85253, United States

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Premier Health
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Centerville, Ohio, 45459, United States

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Premier Neurology
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Greenville, South Carolina, 29605, United States

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Rush University Medical Center
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Chicago, Illinois, 60607, United States

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Sanford Health
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Fargo, North Dakota, 58122, United States

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Saturn Research Solutions LLC
RECRUITING

Plano, Texas, 75024, United States

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Sibyl Wray MD Neurology PC
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Knoxville, Tennessee, 37922, United States

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Tallahassee Neurological Clinic
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Tallahassee, Florida, 32308, United States

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Tufts Medical Center
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Boston, Massachusetts, 02111, United States

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Univ of Cincinnati Medical Center
RECRUITING

Cincinnati, Ohio, 45219, United States

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Univ of Texas Southwest Med Center
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Dallas, Texas, 75390-9034, United States

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University Of South Florida
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Tampa, Florida, 33612, United States

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University of Florida
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Gainesville, Florida, 32610, United States

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University of Kansas Hospital
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Kansas City, Kansas, 66160, United States

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University of New Mexico
RECRUITING

Albuquerque, New Mexico, 87131-0001, United States

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Velocity Clinical Research
RECRUITING

Raleigh, North Carolina, 27607, United States

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Vero Beach Neurology
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Vero Beach, Florida, 32960, United States

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WA Uni School Of Med
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St Louis, Missouri, 63110, United States

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Conditions

Explore the condition pages connected to this study.

RELAPSING MULTIPLE SCLEROSIS