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New inhaled therapy for cystic fibrosis shows promise in early trial

NCT ID NCT03375047

First seen Feb 10, 2026 · Last updated May 22, 2026 · Updated 14 times

Summary

This early-stage study tested an experimental drug called MRT5005, given as a mist through a nebulizer, in 42 adults with cystic fibrosis. The main goal was to check if the treatment is safe and tolerable. Researchers also looked at whether it could improve lung function. The study was completed, and results help guide future research on this potential therapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Johns Hopkins University

    Baltimore, Maryland, 21287, United States

  • Maine Medical Center

    Portland, Maine, 04102, United States

  • National Jewish Health

    Denver, Colorado, 80206, United States

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • New Orleans Center for Clinical Research

    Knoxville, Tennessee, 37920, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Oregon Health and Sciences University

    Portland, Oregon, 97239, United States

  • University Hospitals

    Cleveland, Ohio, 44106, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45267, United States

  • University of Florida

    Gainesville, Florida, 32610, United States

  • University of Indiana

    Indianapolis, Indiana, 46202, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Utah

    Salt Lake City, Utah, 84132, United States

  • Virginia Commonwealth University

    Richmond, Virginia, 23298, United States

Conditions

Explore the condition pages connected to this study.