Can MRI spot radiation damage in the mouth? new study aims to find out
NCT ID NCT06586892
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 26 times
Summary
This study is testing whether a special MRI scan can accurately detect and track damage to the mouth and jaw caused by radiation therapy for head and neck cancer. Researchers will enroll 300 adults who are scheduled for radiation, and give them additional MRI scans before and after treatment. The goal is to validate this imaging method as a reliable tool for diagnosing and monitoring orodental injury, which could help doctors manage this painful side effect.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The University of Texas M. D. Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MRI scan
What this could lead to
If successful, this could provide a reliable, non-invasive way to detect and monitor orodental damage from radiotherapy, improving patient care.
What could go wrong
This is an early validation study focused on imaging accuracy, not a treatment. The MRI technique may not prove sufficiently accurate or practical for routine use.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.