New MRI technique could predict bone damage from cancer radiation
NCT ID NCT03145077
First seen Nov 03, 2025 · Last updated Jun 19, 2026 · Updated 24 times
Summary
This study tests whether a special MRI scan (DCE-MRI) can detect early signs of bone damage caused by radiation therapy in head and neck cancer patients. Researchers will scan 1,400 participants before, during, and after radiation to see if the MRI can predict osteoradionecrosis, a painful condition where jawbone tissue dies. The goal is to improve diagnosis and help doctors adjust treatment to prevent this complication.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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M D Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors predict and prevent bone damage (osteoradionecrosis) in head and neck cancer patients receiving radiation therapy.
What could go wrong
This is an observational study, not a treatment trial. It may not lead to immediate clinical changes, and results depend on MRI accuracy and patient follow-up.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.