MRI study seeks brain clues in metabolic disease
NCT ID NCT06709846
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study uses MRI scans to look for brain differences in people with metabolic diseases compared to healthy volunteers. Researchers will track changes over time and link them to body fat and other health measures. About 126 adults will take part at Ulm University Hospital. No drugs or treatments are being tested.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better understand how metabolic diseases affect the brain over time.
- What could go wrong
- This is an observational study, not a treatment trial. It may not lead to any direct medical benefit for participants.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 126 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Feb 2025
- Expected to finish
-
Dec 2029
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Besides healthy controls, we will include patients who are treated for metabolic diseases at Ulm University Hospital. After the scan for cross-sectional assessment (baseline), patients who are clinically followed up at Ulm University Hospital will be offered follow-up scans, depending on changes in body weight or metabolism.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * patients with metabolic diseases OR * healthy control participants without metabolic diseases * written consent Exclusion Criteria: * History of traumatic brain injuries * preterm birth (≤34th week of pregnancy) of the study participant * history of brain surgery * structural brain changes (e.g., tumors, congenital abnormalities, etc.) * neurological developmental disorders (e.g., autism spectrum disorders, learning disabilities, intellectual disability) * epilepsy, * drug addiction * other severe neurological or severe psychiatric disorders (e.g., schizophrenia * pregnancy * acute clinically relevant inflammatory diseases * acute systemic or local infections * severe or etiologically unclear diseases depending on the principle investigators judgement * pre-existing intellectual impairment * significant limitations in language comprehension * absence of written consent * general exclusion criteria for MRI imaging (e.g., pacemaker systems, neurostimulators, cochlear implants)
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Metabolic diseases are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
University Hospital Ulm
RECRUITINGUlm, 89081, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can tiny tablets replace protein powder for kids with PKU?
- Childhood brain tumor survivors face hidden hormone risks years later
- Could muscle proteins reveal hidden muscle loss in diabetes and obesity?
- Could a metabolic modulator help people with type 1 diabetes use insulin better?
- Gene hunt in children could unlock secrets of rare metabolic diseases
- Could a simple breath test spot hidden diseases early?