Can special MRIs predict cancer treatment outcomes?
NCT ID NCT00581906
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study uses three advanced MRI techniques to see if they can predict how well head and neck cancer patients will respond to surgery or chemo-radiation. About 272 adults with head and neck cancer will get these scans before and early during treatment. The goal is to find markers that help doctors personalize care and improve outcomes.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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272 people
The number who actually took part.
- Start date
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Feb 2006
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Potential research subjects will be identified by a member of the patient's treatment team, the protocol investigator, or research team at Memorial Sloan-Kettering Cancer Center (MSKCC).
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with histologically proven diagnosis of head and neck cancer or patients with tumors strongly suspicious for head and neck cancer due to clinical features or FNA (fine needle aspiration) cytology assessment. * Will undergo surgery or chemo-radiation treatment * Patients must be 18 years or older and have the ability to give informed consent Exclusion Criteria: * Claustrophobia * Known reaction to Gd-DTPA * Pre-operative radiation to primary tumor site * Contraindication to MRI 1. Pacemaker 2. Aneurysmal clips 3. Metal implants in field of view 4. Pregnant or nursing women 5. Age and mental status wherein he/she is unable to cooperate for MRI study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Memorial Sloan-Kettering Cancer Center
New York, New York, 10065, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Sharper tumor maps: PET scans could tighten radiation beams
- Five days of radiation instead of weeks: a new test for head and neck cancer
- Can an online program ease the burden on cancer caregivers?