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MRI may reduce unnecessary biopsies for prostate cancer patients

NCT ID NCT04692675

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 32 times

Summary

This study looks at whether advanced MRI scans (mpMRI) can better track prostate cancer in men who choose active surveillance instead of immediate treatment. About 500 men with low-risk prostate cancer will have regular MRIs alongside standard tests like PSA blood tests and biopsies. The goal is to see if MRI can predict cancer progression more accurately, potentially reducing the number of invasive biopsies needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

multiparametric magnetic resonance imaging (mpMRI)

What this could lead to

If successful, this could show that mpMRI helps doctors monitor prostate cancer more accurately during active surveillance, possibly reducing the need for frequent biopsies.

What could go wrong

This is an observational study, not a treatment trial. It may not change current practice, and results depend on how well imaging matches biopsy findings.

Conditions

The condition(s) this trial relates to.

Disease Progression prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.