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Can a plant compound soothe post-surgery hemorrhoid pain?

NCT ID NCT07647172

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a supplement called MPFF (micronized purified flavonoid fraction) can help reduce pain and improve quality of life in adults with grade 2 or 3 hemorrhoids who are having a minor surgical procedure. About 200 participants will take MPFF as part of their standard care. The main goal is to measure changes in pain levels one week after surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

patients with haemorrhoids undergoing minimally invasive surgical interventions

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Males and females aged over 18 years. * Informing the patient in writing about the inclusion in the study and his/her consent to participate in it. * Absence of conditions requiring urgent medical care. * The patient was diagnosed with chronic hemorrhoids of grade 2 or 3 according to Goligher classification. * The patient is scheduled to undergo one of the listed types of minimally invasive surgical treatment within 7 ± 2 days from the inclusion in the study (V0): * laser vaporization (laser submucosal destruction or ablation); * transanal dearterialization (hemorrhoidal artery ligation); * transanal dearterialization + laser vaporization (laser submucosal destruction or ablation); * transanal dearterialization + sclerotherapy. * No venoactive drug treatment within 4 weeks prior to inclusion in the study. * The patient has been prescribed with MPFF at the inclusion visit, or it is planned to prescribe MPFF-containing drug in the postoperative period (for cluster 1 sites), or the patient has not been prescribed with any systemic venoactive drug, and it is not planned to prescribe it the postoperative period (for cluster 2 sites).\* Exclusion Criteria: * Pregnancy or breast-feeding, or planning for pregnancy during the study or at least in two months after its completion. * Confirmed or suspected malignancy. * Severe somatic disorder (of heart or blood vessels, lungs, kidneys, pancreas, or liver), accompanied by the organ function decompensation. * Mental disorder. * Contraindications for examination. * Predicted unwillingness of the patient to follow the protocol of treatment and supervision, poor adherence to treatment. * Patient's participation in any interventional/observational study at the present time. * Patients who received venoactive drugs in the 4 weeks prior to Visit 0 (inclusion visit).

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

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  1. The official record

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