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Can a Ceramide-Rich moisturizer beat petrolatum for aging skin?

NCT ID NCT07739355

Symptom relief Sponsor: Dr. dr. Lili Legiawati, SpKK(K) Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 31, 2026 · Last updated Jul 31, 2026

Summary

This clinical trial compares a moisturizer containing 5% hydro-urea, ceramide, and MultiVesicular Emulsion technology against plain petrolatum for treating dry skin in people aged 60 and older. The study measures changes in skin dryness, moisture, water loss, itching, and quality of life over the treatment period. It also tracks any side effects like irritation or allergic reactions. The goal is to see if this advanced moisturizer offers better relief and comfort than the standard petrolatum ointment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A moisturizer containing 5% hydro-urea, ceramide, and MultiVesicular Emulsion (MVE) technology
What this could lead to
If effective, this moisturizer could offer a more targeted, comfortable option for managing dry skin in older adults, potentially improving skin hydration and quality of life.
What could go wrong
The trial is small (48 participants) and early-stage, so results may not apply broadly. The moisturizer could cause irritation or allergic reactions in some users.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

48 people

The number who actually took part.

Started

Nov 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * individuals aged 60 years or older who have been diagnosed with clinically dry skin (indicated by SRRC score ranging from 5 to 16), have not used topical moisturizers for at least 2 weeks and oral moisturizing supplements for at least 4 weeks prior, willingness to comply with the research procedures, able to communicate well, and provide written consent by signing the informed consent from. Exclusion Criteria: * individuals with a previous record of hypersensitivity to the moisturizer, dermatitis, or other skin disease affecting the lower extremities, and those with an erythema/fissure score greater than 2 based on SRRC.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dry skin in the elderly

Contacts and locations

Locations

  • Universitas Indonesia, Jakarta Pusat, Jakarta 10430

    Jakarta Pusat, Jakarta Special Capital Region, 10430, Indonesia

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