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New surgical position may protect brain during laparoscopic surgery

NCT ID NCT07632287

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two different patient positions during laparoscopic gynecological surgery to see which one better protects brain oxygen levels and reduces eye nerve pressure. Researchers monitored 70 patients using non-invasive sensors to measure brain oxygenation and eye nerve diameter. The goal was to see if a modified position with bent legs is safer than the standard head-down tilt position.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to safer surgical positioning that reduces brain pressure and improves patient outcomes during laparoscopic procedures.
What could go wrong
This is a small, completed study with only 70 participants, so results may not apply to all patients or surgeries. The modified position may not show significant benefits over the standard one.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

70 people

The number who actually took part.

Started

Mar 2026

Finished

May 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adult patients up to 80 years of age who \[are admitted to the intensive care unit / are undergoing elective surgery / present to the emergency department\]. The population excludes patients with known increased intracranial pressure, severe cerebrovascular, cardiovascular, or pulmonary diseases, morbid obesity (BMI \> 35 kg/m\^2), pregnancy, and any pre-existing ocular pathologies that could affect optic nerve sheath diameter (ONSD)

Ages

18 to 80 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patients aged between 18 and 70 years American Society of Anesthesiologists (ASA) physical status I or II Scheduled for elective laparoscopic surgery requiring Trendelenburg position Provided written informed consent Exclusion Criteria: Patient refusal to participate History of severe cerebrovascular disease Known increased intracranial pressure Pre-existing ocular pathology that could affect optic nerve sheath diameter (ONSD) measurements (e.g., glaucoma, optic neuritis, ocular trauma) Severe cardiovascular or pulmonary disease Body Mass Index (BMI) greater than 35 kg/m\^2 Pregnancy

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Conditions

The condition(s) this trial relates to.

Pneumoperitoneum

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ankara Etlik City Hospital

    Ankara, Ankara, 06010, Turkey (Türkiye)

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Other studies related to the condition(s) this trial covers.